Division Chief, Department of Medicine
Chair, Department of Medicine
Professor, Department of Medicine
Biosketch
Santhosh Koshy, MBBS, DM, MA, MBA, is a board-certified interventional cardiologist and Chair and Professor of the Department of Medicine at Western Michigan University Homer Stryker M.D. School of Medicine in Kalamazoo, Michigan. He is a graduate of University of Kerala Trivandrum Medical College, Thiruvananthapuram, Kerala, India. He completed his first internship, residency, and cardiology fellowship with University of Kerala Trivandrum Medical College, as well. Dr. Koshy then came to the United States, completing an internship and internal medicine residency with Saint Louis University School of Medicine, Saint Louis, Missouri. He then completed a fellowship in adult cardiovascular medicine with the University of Missouri, Columbia, Columbia, Missouri. He then completed an additional fellowship in interventional cardiology and peripheral interventions with the University of Alabama-Birmingham, Birmingham, Alabama. He has also earned an MBA from Washington University Olin Business School, Saint Louis, Missouri, a financial management certification from Cornell University, Ithaca, New York, and a master of arts degree in medical law and health policy.
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Education and Training
- MA 2018, Medical Law and Health Policy, School of Law, Hofstra University
- Certification 2016, Financial Management, Cornell University
- MBA 2012, Olin Business School, Washington University in St Louis
- Fellowship 2005, Interventional Cardiology and Peripheral Interventions, School of Medicine, University of Alabama at Birmingham
- Fellowship 2003, Adult Cardiovascular Medicine, School of Medicine, University of Missouri-Columbia
- Residency 2000, Internal Medicine, School of Medicine, Saint Louis University
- Internship 1998, Internal Medicine, School of Medicine, Saint Louis University
- Fellowship 1997, Adult and Pediatric Cardiovascular Medicine, Trivandrum Medical College, University of Kerala
- Residency 1994, Internal Medicine, Trivandrum Medical College, University of Kerala
- Internship 1991, Trivandrum Medical College, University of Kerala
- MBBS 1991, Trivandrum Medical College, University of Kerala
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Research
- Interventional Cardiology
- Cardiovascular Imaging
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Publications
Jeyaraman M., John A., Koshy S., Ranjan R., Anudeep T.C., Jain R., Swati K., Jha N.K., Sharma A., Kesari K.K., Prakash A., Nand P., Jha S.K., Reddy P.H. Fostering mesenchymal stem cell therapy to halt cytokine storm in COVID-19 Biochimica et Biophysica Acta - Molecular Basis of Disease. 2021;1867(2)
Tharakan A., Shukla H., Benny I.R., Tharakan M., George L., Koshy S. Immunomodulatory effect of withania somnifera (Ashwagandha) extract—A randomized, double-blind, placebo controlled trial with an open label extension on healthy participants Journal of Clinical Medicine. 2021;10(16)
Agarwal M.A., Potukuchi P.K., Sumida K., Naseer A., Molnar M.Z., George L.K., Koshy S.K., Streja E., Thomas F., Kalantar-Zadeh K., Kovesdy C.P. Clinical Outcomes of Warfarin Initiation in Advanced Chronic Kidney Disease Patients With Incident Atrial Fibrillation JACC: Clinical Electrophysiology. 2020;6(13):1658-1668.
Koshy S.K.G., George L.K., Das P. Cost-effectiveness and Outcomes with Early or Same-Day Discharge After Elective Percutaneous Coronary Intervention Current Cardiology Reports. 2020;22(6)
Akinseye O.A., Haji S.A., Koshy S.K.G., Ibebuogu U.N., Khouzam R.N., Garg N. Outcomes of Percutaneous Antegrade Intraluminal Coronary Intervention of Chronic Total Occlusion With Remote Surgical Backup Current Problems in Cardiology. 2019;44(12)
Almaddah N., Najib K., Shahreyar M., Holden A., Koshy S., Khouzam R., Garg N. Left Anterior Descending Coronary Artery Occlusion Resulting From Concussion by a Bullet Annals of Thoracic Surgery. 2019;107(2):e137.
Gaipov A., Molnar M.Z., Potukuchi P.K., Sumida K., Canada R.B., Akbilgic O., Kabulbayev K., Szabo Z., Koshy S.K.G., Kalantar-Zadeh K., Kovesdy C.P. Predialysis coronary revascularization and postdialysis mortality Journal of Thoracic and Cardiovascular Surgery. 2019;157(3):976-983.e7.
Gaipov A., Molnar M.Z., Potukuchi P.K., Sumida K., Szabo Z., Akbilgic O., Streja E., Rhee C.M., Koshy S.K.G., Canada R.B., Kalantar-Zadeh K., Kovesdy C.P. Acute kidney injury following coronary revascularization procedures in patients with advanced CKD Nephrology Dialysis Transplantation. 2019;34(11):1894-1901.
Koshy S.K.G., George E., George L.K. Value of echocardiogram in predicting sudden cardiac death: A look beyond ejection fraction Echocardiography. 2019;36(3):431-432.
Koshy S.K.G., George M.K., George L.K. Value of early detection of left ventricular mechanical dyssynchrony for assessing long-term outcomes Echocardiography. 2019;36(11):1970-1971.
Harper Y., Salem S., Alsafwah S., Koshy S., Garg N. When the gold standard is not always golden: The value of invasive hemodynamic assessment to overcome the pitfalls of echocardiography in challenging cases of mitral stenosis Echocardiography. 2018;35(1):104-109.
Koshy S.K.G., George K.K., George L.K. Changes in right ventricular morphology and function in athletes Echocardiography. 2018;35(6):767-768.
Morsy M., Slomka T., Shukla A., Uppal D., Bomb R., Akinseye O.A., Koshy S.K.G., Garg N. Clinical and echocardiographic predictors of new-onset atrial fibrillation in patients admitted with blunt trauma Echocardiography. 2018;35(10):1519-1524.
Shahreyar M., Salem S., Nayyar M., George L., Garg N., Koshy S. Hyperlipidemia: Management with proprotein convertase subtilisin/kexin type 9 (PCSK9) Inhibitors Journal of the American Board of Family Medicine. 2018;31(4):628-634.
George L.K., Koshy S.K.G., Molnar M.Z., Thomas F., Lu J.L., Kalantar-Zadeh K., Kovesdy C.P. Heart Failure Increases the Risk of Adverse Renal Outcomes in Patients with Normal Kidney Function Circulation: Heart Failure. 2017;10(8)
George L.K., Molnar M.Z., Lu J.L., Kalantar-Zadeh K., Koshy S.K.G., Kovesdy C.P. Association of Pre-Operative Albuminuria with Post-Operative Outcomes after Coronary Artery Bypass Grafting Scientific Reports. 2015;5
Koshy S., George L. Predicting left ventricular function recovery after reperfusion in ST elevation myocardial infarction: Can we balance cost and accuracy? Echocardiography. 2015;32(4):613-614.
Koshy S., Govindarajan G. Microvascular dysfunction in systemic diseases: How does it relate to chagas' disease? Echocardiography. 2014;31(1):1-2.
Koshy S., Khouzam R., Govindarajan G. Noninvasive coronary flow reserve evaluation of coronary stenosis detected by multislice computed tomography: A value added proposition? Echocardiography. 2013;30(3):248-249.
Koshy S., Shaheen M., Khouzam R.N. Spontaneous Dissection of All 3 Coronary Arteries in a Postpartum Woman Canadian Journal of Cardiology. 2013;29(3):403.e3-403.e4.
John J., Koshy S. Current oral antiplatelets: Focus update on prasugrel Journal of the American Board of Family Medicine. 2012;25(3):343-349.
Koshy S., Govindarajan G. Rationale and pitfalls of noninvasive coronary flow reserve estimation in assessment of microvascular disease Echocardiography. 2012;29(6):631-633.
Shaheen M.H., Das P., Koshy S.K.G., Jha S.K., Kabra R. An anticoagulation option for nonvalvular atrial fibrillation Journal of Family Practice. 2012;61(6)
Ali S., George L., Das P., Koshy S. Intracardiac echocardiography: Clinical utility and application Echocardiography. 2011;28(5):582-590.
Nair M., George L., Koshy S. Safety and efficacy of ibutilide in cardioversion of atrial flutter and fibrillation Journal of the American Board of Family Medicine. 2011;24(1):86-92.
Robinson A., Das K., Koshy S.K.G., Das P. Prasugrel: Newest antiplatelet agent and its emerging role in management of acute coronary syndrome and percutaneous coronary intervention Future Cardiology. 2009;5(3):237-246.
Koshy S.K.G., Kleiman N.S., George L.K., Misra V., Hillegass W.B., Brott B.C. Vascular changes and black hole phenomenon after coronary brachytherapy: A pathologically distinct entity Journal of Invasive Cardiology. 2008;20(10):560-562.
Dokainish H., Gonzalez R., Hartley W., Caldera A., Koshy S., Sengupta R., Lakkis N. Usefulness of B-Type Natriuretic Peptide Levels to Predict Left Ventricular Filling Pressures in Patients With Body Mass Index >35, 31 to 35, and ≤30 kg/m<sup>2</sup> American Journal of Cardiology. 2007;100(7):1166-1171.
Reddy H.K., Koshy S.K.G., Wasson S., Quan E.E., Pagni S., Roberts A.M., Joshua I.G., Tyagi S.C. Adaptive-outward and maladaptive-inward arterial remodeling measured by intravascular ultrasound in hyperhomocysteinemia and diabetes Journal of Cardiovascular Pharmacology and Therapeutics. 2006;11(1):65-76.
Reddy H., Koshy S., Foerst J., Sturek M. Remodeling of Coronary Arteries in Diabetic Patients - An Intravascular Ultrasound Study Echocardiography. 2004;21(2):139-144.
Reddy H.K., Koshy S.K.G., Wasson S., Aggarwal K.B., Tejwani L., Ovechkin A.V., Tyagi S.C. Echocardiography predicts adverse cardiac remodelling in heart failure Experimental and Clinical Cardiology. 2004;9(2):112-116.
Koshy S.K.G., Reddy H.K., Shukla H.H. Collagen cross-linking: New dimension to cardiac remodeling Cardiovascular Research. 2003;57(3):594-598.
Reddy H.K., Koshy S.K.G., Shukla H. Erratum: Triggers and promoters of ischaemic preconditioning (Cardiovascular Research (2002) 56 (1-3) PII: S0008-6363(02)00605-3) Cardiovascular Research. 2003;59(3):798.
Reddy H.K., Wasson S., Koshy S.K.G., Komatireddy R. Structural correlates of electrical remodeling in ventricular hypertrophy Cardiovascular Research. 2003;58(3):495-497.
Reddy H.K., Koshy S.K.G., Shukia H. Triggers and promoters of ischaemic preconditioning Cardiovascular Research. 2002;56(1):1-3.
Reddy H.K., Koshy S.K.G., Sturek M., Jayam V.K., Bedi A., McCullough P. Rationale and methods for assessment of coronary flow prior to coronary intervention: Where are we headed? Journal of Interventional Cardiology. 2002;15(4):335-341.