Clinical Assistant Professor, Department of Medicine
Biosketch
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Board Certification
- American Board of Internal Medicine (Internal Medicine)
- American Board of Internal Medicine (Sleep Medicine)
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Education and Training
- Residency 2009, Primary Care/Internal Medicine, Yale New Haven Hospital/Waterbury Hospital, Yale University
- MD 2006, Albert Einstein College of Medicine/Yeshiva University, Yeshiva University
- BS 2001, Biological Sciences, University of California-Irvine
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Publications
Chang H., Locker J., Lu R., Schuster V. Failure of postnatal ductus arteriosus closure in prostaglandin transporter-deficient mice Circulation. 2010;121(4):529-536.
Finnegan E., Barabino G., Liu X., Chang H., Jonczyk A., Kaul D. Small-molecule cyclic αVβ3 antagonists inhibit sickle red cell adhesion to vascular endothelium and vasoocclusion American Journal of Physiology - Heart and Circulatory Physiology. 2007;293(2)
Dobrenis K., Chang H.Y., Pina-Benabou M.H., Woodroffe A., Lee S.C., Rozental R., Spray D.C., Scemes E. Human and mouse microglia express connexin36, and functional gap junctions are formed between rodent microglia and neurons Journal of Neuroscience Research. 2005;82:306-315.
Nomura T., Chang H., Lu R., Hankin J., Murphy R.C., Schuster V.L. Prostaglandin signaling in the renal collecting duct: Release, reuptake, and oxidation in the same cell Journal of Biological Chemistry. 2005;280(31):28424-28429.
Kaul D., Liu X., Chang H., Nagel R., Fabry M. Effect of fetal hemoglobin on microvascular regulation in sickle transgenic-knockout mice Journal of Clinical Investigation. 2004;114(8):1136-1145.
Chang H., Hua L.L., Morgan A., Lee S.C. Inhibition of astrocyte TNFα expression by extracellular potassium Brain Research. 2001;888(1):176-179.
Morgan A.C.A., Chang H., Liu J.S.H., Hua L.L., Lee S.C. High extracellular potassium modulates nitric oxide synthase expression in human astrocytes Journal of Neurochemistry. 2000;74(5):1903-1912.
Roth E., Wenz B., Lee H., Fabry M., Chang H., Kaul D., Baez S., Nagel R. Survival rates and properties of sickle cell anemia red cells treated with nitrogen mustard. Progress in clinical and biological research. 1987;240:245-261.
Chang H., Ewert S., Nagel R. Identification of 2-imidazolines as anti-sickling agents Molecular Pharmacology. 1983;23(3):731-734.
Chang H., Ewert S.M., Bookchin R.M., Nagel R.L. Comparative evaluation of fifteen anti-sickling agents Blood. 1983;61(4):693-704.
Chang H., Suzuka S. Lawsone (2-OH-1,4-naphthoquinone) derived from the henna plant increases the oxygen affinity of sickle cell blood Biochemical and Biophysical Research Communications. 1982;107:602-608.
Fabry M., Kaul D., Raventos-Suarez C., Chang H., Nagel R. SC erythrocytes have an abnormally high intracellular hemoglobin concentration. Pathophysiological consequences Journal of Clinical Investigation. 1982;70(6):1315-1319.
Nagel R.L., Chang H. Methods for the Study of Sickling and Hemoglobin S Gelation Methods in Enzymology. 1981;76:760-792.