Adjunct Research Assistant Professor, Department of Investigative Medicine
Adjunct Research Assistant Professor, Department of Pediatric and Adolescent Medicine
Biosketch
Dr. Sharon Singh is an Adjunct Research Assistant Professor with the Departments of Biomedical Sciences and Pediatric and Adolescent Medicine. She currently is a member of the Rothstein Lab in the Center for Immunology. She is Board Certified in Pediatric Hematology-Oncology. She is employed by the Bronson Healthcare Group. Dr. Singh is a graduate of New York University with a BA in Chemistry in May 1997. She earned her MD from New York University Mount Sinai School of Medicine in May 2001. She completed her Pediatric residency with Schneider Children's Hospital at North Shore (now known as Cohen Children's Medical Center) in June 2004. She completed her Fellowship in Pediatric Hematology and Oncology also with Schneider Children's Hospital (now known as Cohen Children's Medical Center)
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Board Certification
- American Board of Pediatrics (General Pediatrics)
- American Board of Pediatrics (Pediatric Hematology-Oncology)
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Education and Training
- Fellowship 2008, Pediatric Hematology and Oncology, Schneider Children's Hospital
- Residency 2004, Pediatrics, Schneider Children's Hospital at North Shore
- MD 2001, Mount Sinai School of Medicine, New York University
- BA 1997, Chemistry, College of Arts and Sciences, New York University
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Language Fluency
- Spanish, functional
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Research
- General Pediatrics
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Publications
Kadouh N.K., Lang S., Shamoun M., Scott E.L., Singh S.A., Smith M.A. Mexiletine: An adjuvant option for refractory pain in patients with sickle cell disease and comorbid autism spectrum disorder Pediatric Blood and Cancer. 2022;69
Yu L., Myers G., Schneider E., Wang Y., Mathews R., Lim K.C., Siemieniak D., Tang V., Ginsburg D., Balbin-Cuesta G., Singh S.A., Phuwakanjana P., Jearawiriyapaisarn N., Khoriaty R., Engel J.D. Identification of novel γ-globin inducers among all potential erythroid druggable targets Blood Advances. 2022;6:3280-3285.
Irwin M., Gunther W., Keefer P., Saul D.A., Singh S.A., Wright J., Smith M.A. Buprenorphine for Chronic Pain in a Pediatric Patient With Sickle-Cell Disease Journal of Pain and Symptom Management. 2021;62:1086-1091.
Ludlow A., George N., Glassford M., Udenberg K., Hannibal M.C., Schwalm C., Scott K., Rothstein T.L., Singh S.A. The Use of B-Cell Polysome Profiling to Validate Novel RPL5 (uL18) and RPL26 (uL24) Variants in Diamond-Blackfan Anemia Journal of Pediatric Hematology/Oncology. 2021;43:e336-e340.
Wang Y., Yu L., Engel J.D., Singh S.A. Epigenetic activities in erythroid cell gene regulation Seminars in Hematology. 2021;58:4-9.
Yu L., Lemay P., Ludlow A., Guyot M.C., Jones M., Mohamed F.F., Saroya G.A., Panaretos C., Schneider E., Wang Y., Myers G., Khoriaty R., Li Q., Franceschi R., Engel J.D., Kaartinen V., Rothstein T.L., Justice M.J., Kibar Z., Singh S.A. A new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia Blood Advances. 2021;5:4167-4178.
Yu L., Myers G., Ku C.J., Schneider E., Wang Y., Singh S.A., Jearawiriyapaisarn N., White A., Moriguchi T., Khoriaty R., Yamamoto M., Rosenfeld M.G., Pedron J., Bushweller J.H., Lim K.C., Engel J.D. An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation Blood. 2021;138:1691-1704.
Singh S.A., Bakshi N., Mahajan P., Morris C.R. What is the future of patient-reported outcomes in sickle-cell disease? Expert Review of Hematology. 2020;13:1165-1173.
Singh S.A., Sarangi S., Appiah-Kubi A., Hsu P., Smith W., Gallagher P.G., Glader B., Chui D.H.K. Hb Adana (HBA2 or HBA1: c.179G > A) and alpha thalassemia: Genotype–phenotype correlation Pediatric Blood and Cancer. 2018;65
Dulmovits B.M., Appiah-Kubi A.O., Papoin J., Hale J., He M., Al-Abed Y., Didier S., Gould M., Husain-Krautter S., Singh S.A., Chan K.W.H., Vlachos A., Allen S.L., Taylor N., Marambaud P., An X., Gallagher P.G., Mohandas N., Lipton J.M., Liu J.M., Blanc L. Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors Blood. 2016;127:1481-1492.
Wood J.C., Cohen A.R., Pressel S.L., Aygun B., Imran H., Luchtman-Jones L., Thompson A.A., Fuh B., Schultz W.H., Davis B.R., Ware R.E., George A., Mueller B.U., Heeney M.M., Kalfa T.A., Nelson S., Clark Brown R., Gee B., Kwiatkowski J.L., Smith- Whitley K., Odame I., Webb J., Yang E., Lee M.T., Piccone C., Jackson S.M., Singh S., Nottage K., Hankins J.S., Miller S.T., Hilliard L., Alvarez O., Rhodes M., Rogers Z.R., Sarnaik S.A., Owen W.C., Gauger C., Roberts C., Rothman J.A. Organ iron accumulation in chronically transfused children with sickle cell anaemia: Baseline results from the TWiTCH trial British Journal of Haematology. 2016;172:122-130.
Singh S.A., Goldberg T.A., Henson A.L., Husain-Krautter S., Nihrane A., Blanc L., Ellis S.R., Lipton J.M., Liu J.M. p53-independent cell cycle and erythroid differentiation defects in murine embryonic stem cells haploinsufficient for Diamond Blackfan anemia-proteins: RPS19 versus RPL5 PLoS ONE. 2014;9
Sezgin G., Henson A.L., Nihrane A., Singh S., Wattenberg M., Alard P., Ellis S.R., Liu J.M. Impaired growth, hematopoietic colony formation, and ribosome maturation in human cells depleted of Shwachman-Diamond syndrome protein SBDS Pediatric Blood and Cancer. 2013;60:281-286.
Vlachos A., Farrar J.E., Atsidaftos E., Muir E., Narla A., Markello T.C., Singh S.A., Landowski M., Gazda H.T., Blanc L., Liu J.M., Ellis S.R., Arceci R.J., Ebert B.L., Bodine D.M., Lipton J.M. Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q- Syndrome Blood. 2013;122:2487-2490.
Aygun B., Wruck L.M., Schultz W.H., Mueller B.U., Brown C., Luchtman-Jones L., Jackson S., Iyer R., Rogers Z.R., Sarnaik S., Thompson A.A., Gauger C., Helms R.W., Ware R.E., Mueller B., Dinu B., Viswanathan K., Sommerville-Brooks N., Record B., Heeney M., Anderson M., Kwiatkowski J.L., Olson J., Brown M., Krishnamurti L., McCollum R., Godder K., Newlin J., Owen W., Nelson S., Bianchi K., Brown S., Lee M., Thornburg C., Daeschner C., Kuisel L., Nagasubramanian R., Berman B., DeBarr M., Singh S., Farrell A., Hansbury E., Miller S., Rey K., Odame I., Parmar N., Merelles-Pulcinni M., Adix L., Hilliard L., Dumas J., Neier M., Farias S., Ofelia Alvarez , Patrice Williams , Walker M.T., Imran H., Durggin S., Yang E., Murphy M. Chronic transfusion practices for prevention of primary stroke in children with sickle cell anemia and abnormal TCD velocities American Journal of Hematology. 2012;87:428-430.
Singh S.A., Vlachos A., Morgenstern N.J., Ouansafi I., Ip W., Rommens J.M., Durie P., Shimamura A., Lipton J.M. Breast cancer in a case of Shwachman Diamond syndrome Pediatric Blood and Cancer. 2012;59:945-946.
Singh S., Koumbourlis A., Aygun B. Resolution of chronic hypoxemia in pediatric sickle cell patients after treatment with hydroxyurea Pediatric Blood and Cancer. 2008;50:1258-1260.