Assistant Professor, Department of Biomedical Sciences
Biosketch
Holly Turula, PhD, received her undergraduate degree in biology from Portland State University, Portland, Oregon. She trained in viral immunology both at Oregon Health and Science University, Portland, Oregon, and at Thomas Jefferson University, Philadelphia, Pennsylvania, before completing her doctorate in immunology at The University of Michigan, Ann Arbor, Michigan. For her postdoctoral training, she accepted an Institutional Research and Academic Career Development Award (IRACDA) at the University of Michigan in the Department of Microbiology and Immunology where she focused on education and research in the field of microbiology.
-
Education and Training
- PhD 2019, Immunology, University of Michigan-Ann Arbor
- BS 2008, Biology, Portland State University
-
Research
- molecular immunology
- Virology
- Norovirus
- Microscopy, Fluorescence
- Macrophages
- Immunoglobulin A, Secretory
- Immunity, Mucosal
- Cytomegalovirus Infections
- Cell Biology
-
Publications
Mirabelli C., Jones M.K., Young V.L., Kolawole A.O., Owusu I., Shan M., Abuaita B., Turula H., Trevino J.G., Grigorova I., Lundy S.K., Lyssiotis C.A., Ward V.K., Karst S.M., Wobus C.E. Human Norovirus Triggers Primary B Cell Immune Activation In Vitro mBio. 2022;13
Grau K.R., Zhu S., Peterson S.T., Helm E.W., Philip D., Phillips M., Hernandez A., Turula H., Frasse P., Graziano V.R., Wilen C.B., Wobus C.E., Baldridge M.T., Karst S.M. The intestinal regionalization of acute norovirus infection is regulated by the microbiota via bile acid-mediated priming of type III interferon Nature Microbiology. 2020;5(1):84-92.
Smith C.J., Venturi V., Quigley M.F., Turula H., Gostick E., Ladell K., Hill B.J., Himelfarb D., Quinn K.M., Greenaway H.Y., Dang T.H.Y., Seder R.A., Douek D.C., Hill A.B., Davenport M.P., Price D.A., Snyder C.M. Stochastic expansions maintain the clonal stability of CD8<sup>+</sup> T cell populations undergoing memory inflation driven by murine cytomegalovirus Journal of Immunology. 2020;204(1):112-121.
Turula H., Cunha J.B., Mainou B.A., Ramakrishnan S.K., Wilke C.A., Gonzalez-Hernandez M.B., Pry A., Fava J., Bassis C.M., Edelman J., Shah Y.M., Corthesy B., Moore B.B., Wobus C.E. Natural secretory immunoglobulins promote enteric viral infections Journal of Virology. 2018;92(23)
Turula H., Wobus C. The role of the polymeric immunoglobulin receptor and secretory immunoglobulins during mucosal infection and immunity Viruses. 2018;10(5)
Baldridge M., Turula H., Wobus C. Norovirus Regulation by Host and Microbe Trends in Molecular Medicine. 2016;22(12):1047-1059.
Kolawole A.O., Gonzalez-Hernandez M., Turula H., Yu C., Elftman M.D., Wobus C.E. Oral norovirus infection is blocked in mice lacking Peyer's patches and mature M cells Journal of Virology. 2016;90(3):1499-1506.
Quinn M., Turula H., Tandon M., Deslouches B., Moghbeli T., Snyder C.M. Memory T cells specific for murine cytomegalovirus re-emerge after multiple challenges and recapitulate immunity in various adoptive transfer scenarios Journal of Immunology. 2015;194(4):1726-1736.
Smith C., Caldeira-Dantas S., Turula H., Snyder C. Murine CMV Infection Induces the Continuous Production of Mucosal Resident T Cells Cell Reports. 2015;13(6):1137-1148.
Smith C.J., Turula H., Snyder C.M. Systemic Hematogenous Maintenance of Memory Inflation by MCMV Infection PLoS Pathogens. 2014;10(7)
Turula H., Smith C.J., Grey F., Zurbach K.A., Snyder C.M. Competition between T cells maintains clonal dominance during memory inflation induced by MCMV European Journal of Immunology. 2013;43(5):1252-1263.
Doom C., Turula H., Hill A. Investigation of the impact of the common animal facility contaminant murine norovirus on experimental murine cytomegalovirus infection Virology. 2009;392(2):153-161.